NatureU® Now Has Three Clinical Studies Publicly Registered on ClinicalTrials.gov as 56-Day PQQ Skin-Aging Study (NCT07571629) Joins Two Previously Published Peer-Reviewed Trials

Kwun Tong, Kowloon, HK, June 05, 2026 (GLOBE NEWSWIRE) — The newly registered 56-day exploratory research of NatureU® Thoughts Care BeautyU Caps — reporting within-participant adjustments of −46.7% in crow’s-feet wrinkle depend and +58.7% in stratum corneum hydration at Day 56 — joins NatureU’s prior sleep and satiety scientific trials, each already revealed in peer-reviewed journals. The information are exploratory and the brand new research has not but undergone peer evaluation.

OmniSolutions Laboratory Holdings Restricted, the science-driven firm behind the NatureU® (https://natureuhealth.com) nutraceutical model, at the moment introduced that its 56-day exploratory scientific research of NatureU® Thoughts Care BeautyU Caps — a multi-ingredient oral complement containing pyrroloquinoline quinone (PQQ), quercetin, cranberry extract and ergothioneine — has been publicly registered on the U.S. Nationwide Library of Medication’s ClinicalTrials.gov  registry as NCT07571629. With this submitting, three NatureU scientific research now have publicly documented outcomes on the registry. The 2 earlier NCT-registered NatureU trials — masking sustained-release sleep help and participant-reported satiety in weight administration — have already been revealed in peer-reviewed journals.

In regards to the newly registered PQQ research (NCT07571629)

The newly registered trial was a single-center, open-label, single-arm exploratory scientific research carried out at Centre Testing Worldwide Pinbiao (Shanghai) Co., Ltd., an unbiased contract testing group, and reviewed and permitted by the Shanghai CTI Medical Medication Division on January 3, 2025 (approval reference no. A225000034310100101C). Of 33 enrolled wholesome girls aged 36 to 56 years, 31 accomplished all scheduled assessments by means of Day 56 and had been included within the completer efficacy evaluation; two contributors withdrew for private causes unrelated to tolerability. All contributors supplied written knowledgeable consent. The investigational product contained quercetin 100 mg, cranberry extract 100 mg (equal to twenty,000 mg cranberry uncooked materials; standardized to 30 mg proanthocyanidins), PQQ 20 mg and ergothioneine 10 mg per capsule, taken orally as soon as each day for 56 consecutive days.

The prespecified main endpoint was the Day 56 within-participant change from baseline in PRIMOS CR crow’s-feet wrinkle depend. The secondary endpoint was the Day 56 within-participant change from baseline in Corneometer CM 825 stratum corneum hydration. Within the completer inhabitants, PRIMOS CR crow’s-feet wrinkle depend decreased from a imply of 965 ± 334 at baseline to 514 ± 171 at Day 56, a within-participant change of −46.74% (nominal P = 0.001), and Corneometer-measured hydration elevated from 44.3 ± 7.8 to 70.3 ± 9.9, a within-participant change of +58.69% (nominal P = 0.001). The expanded exploratory endpoint set reported within the manuscript consists of Cutometer R2 elasticity (+19.05%), VISIA CR gloss (+47.10%), Colorimeter ITA° (+16.13%), Mexameter melanin index (−14.79%), VISIA CR spot space ratio (−15.52%) and DermaScan dermal thickness (+16.36%) and density (+5.36%) at Day 56 (all nominal P ≤ 0.003). No hostile reactions had been reported throughout the 56-day intervention. P values are reported as nominal values; no formal multiplicity correction was utilized. Reporting follows the TREND (Clear Reporting of Evaluations with Nonrandomized Designs) and TIDieR (Template for Intervention Description and Replication) frameworks. The accompanying manuscript is publicly accessible as a preprint on medRxiv at https://doi.org/10.64898/2026.05.07.26351904 and has not but been peer-reviewed; findings are exploratory and hypothesis-generating.

Two beforehand registered NatureU scientific research already revealed

Alongside at the moment’s registration, two earlier NatureU scientific research are publicly catalogued on ClinicalTrials.gov and have already appeared in peer-reviewed literature. NCT07600528 — NatureU® Candy Dream — was a single-blind exploratory scientific analysis of a sustained-release GABA and α-s1 casein hydrolysate capsule versus industrial melatonin in 15 wholesome adults. Deep-sleep period averaged 130.07 ± 37.07 minutes within the Candy Dream situation versus 96.87 ± 29.half-hour within the melatonin situation (a 34% within-condition distinction; P = 0.01); deep-sleep proportion was 29.13% ± 5.42% versus 22.53% ± 6.16% (P = 0.01). No hostile occasions had been reported. Major outcomes had been revealed within the Worldwide Journal of Medical Case Experiences and Critiques, 30(5)-913, 2025 (DOI: 10.31579/2690-4861/913).

NCT07597382 — NatureU® Burn — was an exploratory scientific analysis of a completed oral complement combining Irvingia gabonensis seed extract and inulin on participant-reported satiety in wholesome adults; main outcomes had been revealed in Present Subjects in Nutraceutical Analysis, Vol. 23, pp. 50–55, 2025 (https://doi.org/10.37290/ctnr2641-452X.23:50-55). Two further NatureU research — NCT07585825 (Cheers Associates Curcumin) and NCT07571616 (Pelvic Well being Pumpkin Seed) — are additionally registered with Accomplished standing; main outcomes haven’t but been publicly reported. All 5 research are interventional and had been funded by OmniSolutions Laboratory Holdings Restricted; co-author disclosures seem within the revealed articles.

About NatureU® and the MASTER™ supply platform

NatureU® merchandise are formulated utilizing OmniSolutions’ MASTER™ (Multistage Adaptive Sustained-Launch Know-how) supply platform, a multi-stage excipient-and-release strategy addressing solubility, stability and pH-responsive intestinal launch, and coated partially by Chinese language invention patent CN117679384A (2024). NatureU® completed merchandise are manufactured in New Zealand and the USA. NatureU® Thoughts Care BeautyU Caps is at the moment offered in Hong Kong by means of Mannings and HKTVmall and in North America by means of the NatureU® brand store on Amazon US.

The investigational product and the corporate’s prior scientific trials mirror a improvement philosophy that pairs published-ingredient rationale with finished-product scientific analysis. NatureU’s three publicly documented research span sleep help, weight administration and skin-aging — three of essentially the most steadily studied consumer-health domains — and are carried out at unbiased contract analysis organizations with ethics-committee oversight.

Limitations and language self-discipline

The NCT07571629 research is exploratory and signal-generating. It was open-label, single-arm, single-center, and was not randomized, not blinded, and never placebo-controlled. Findings needs to be interpreted as hypothesis-generating and require affirmation in randomized, double-blind, placebo-controlled trials earlier than any causal or therapy declare may be made. The manuscript has been posted as a preprint and has not but undergone peer evaluation. NatureU® Thoughts Care BeautyU Caps is a dietary complement; it isn’t supposed to diagnose, deal with, remedy or forestall any illness, and these statements haven’t been evaluated by the U.S. Meals and Drug Administration.

The ClinicalTrials.gov document is accessible at https://clinicaltrials.gov/study/NCT07571629. The medRxiv preprint is out there at https://doi.org/10.64898/2026.05.07.26351904.